In the comedy, which premieres in theaters on Jan. 16, Hart plays the best man for Gad's upcoming onscreen nuptials.
The catch: Socially challenged men need Hart's help - enter the geeky, but adorable Gad.
On the red carpet, both comedians joked with reporters and TV crews as they played off of each others goofiness.
They talked about their favorite wedding moments when Gad asked Hart if he could officiate his upcoming nuptials to girlfriend, Eniko Parish. "No," replied Hart.
Gad, who starred in "Jobs" is familiar with South Florida. He lived in Hollywood and graduated from Nova Southeastern University in 1999. But when asked about his former hangouts and places to eat, he explained through laughter that "I can't recall where I ate as a kid because I was too stoned half of the time," he said.
He married his sweetheart, Ida Darvish in 2008, but has some fond wedding memories that he shared with his female co-star from "Love and Other Drugs."
"Officiating Anne Hathaway's wedding was pretty cool. It was in this remote area in California," he said. "It was stunning and just fun to be able to do something like that. I almost made a career out of that."
Hart has some favorite wedding moments of his own.
"Seeing Dwyane Wade and Gabrielle Union get married, but more importantly see Dwyane's kids be as proud as their father as any other person in the room."